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BM/BMP26: Molecular Microbiology (9 ECTS)

STADS: 1653601

Level
PhD course

Teaching period

Autumn semester

Teacher responsible
Email: kgerdes@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 14-16 U49D 40-41,44-45
Common I Tuesday 16-18 U49D 43
Common I Thursday 13-15 u82 39
Common I Thursday 13-15 U26a 40-41,44
Common I Thursday 16-18 U26a 43
s1 TL Monday 8-16 45-46
s1 TL Tuesday 8-16 45-46
s1 TL Wednesday 8-16 45-46
s1 TL Thursday 8-16 45-46
s1 TL Friday 8-16 45-46
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Comment:
Maksimalt deltagerantal: 26
06.09.2005: Lokale-og skemaændring

Prerequisites:
None

Academic preconditions:
For SDU students: Microbiology (BM115), Prokaryote Molecular Biology (BM114) is recommended. Others: Basic courses in Microbiology and Molecular Biology.

Course introduction
To give a basic understanding of the use of plasmids as experimental systems, as tools for cloning and as tools in analytical molecular biology, and to give understanding of current ideas about DNA replication and cell cycle control in prokaryotes.

Expected learning outcome


Subject overview
  • Expression vectors in model prokaryotes
  • Optimising gene expression
  • Plasmid biology og technology
  • Uses of reporter genes (lacZ, gfp, lux)
  • Use of bioinformatics (phylogeny) in analytical molecular biology
  • Control af plasmid replication and its technological use
  • Control af chromosome replication
  • Cellcycle control, involving:
    • Oscillating proteins
    • Plasmid segregation mechanisms
    • Actin-like proteins in morphogenesis and chromosome segregation
    • Protein-regulated toxin-antitoxin systems
  • Stress response regulons in bacteria
  • Regulatory roles of polyphosphate in bacteria
  • Translational and transcriptional control during physiological stress
Literature
  • Kompendium med artikler. .
  • Øvelsesvejledning. .


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Approval of the laboratory exercises is a prerequisite for participation in the 4-hour written examination where all aids are allowed. External examiner. Grades according to the Danish 13-point scale. Use of computer is not allowed at the exam. There is only examination once a year (January)

Expected working hours
The teaching method is based on three phase model.

Forelæsninger og laboratorieøvelser (20 timer teori og 70 timer laboratorieøvelser).
Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.