KE826: Spectroscopy (5 ECTS)

STADS: 10010501

Level
Master's level course

Teaching period
The course is offered in the autumn semester.

Teacher responsible
Email: mip@sdu.dk

Timetable
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Prerequisites:
The student should be enrolled on a Master programme in chemistry / medicinal chemistry / nanobioscience or a M.Sc. minor in chemistry.

Academic preconditions:
Students taking the course are expected to:

• be able to apply NMR spectroscopy as an analytical tool
• have seen the basic theory of NMR and quantum chemistry
• possess fundamental mathematical abilities

Course introduction
The aim of KE826 is in part to provide an introduction to the theoretical foundation of NMR spectroscopy and in part to provide an understanding of NMR spectroscopy in a context of analytical applications.

The course will for many students be the last focusing on NMR spectroscopy in their education and hence form the basis for applications of NMR spectroscopy in Master projects. In addition the course can provide a basis for further work within NMR research.

The course uses abilities acquired in a basic course in analytical spectroscopy, e.g. KE504, and in basic math courses, as well as in knowledge of quantum chemistry.

In the context of the profile of the education, this course is focused on students acquiring the ability to apply structural-chemical characterisation techniques.

Expected learning outcome
The learning objectives of the course are that the student demonstrates the ability to:

• Identify and analyse 1st and 2nd order spin systems
• Analyse simple pulse sequences using the vector model
• Describe the principles of relaxation
• Explain the principles of 2D NMR spectroscopy and possess knowledge of the most common 2D NMR pulse sequences
• Apply NMR spectroscopy to obtain structural information

Subject overview
The following main topics are contained in the course:

• Spin systems, strong and weak coupling, including AB and ABX
• Relaxation, NOE and dynamic NMR
• Pulse sequences and the vector model
• Principles of 2D NMR and its applications
• NMR of “other” nuclei, including 15N and 31P
• A project

Literature

• Horst Friebolin: Basic One- and Two-Dimensional NMR Spectroscopy, Wiley-VCH.ISBN-nr.: 978-3-527-31233.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam

1. Project report. Passed/not passed, internal marking by lecturer. Approval of the project report is a prerequisite for participating in the written exam. (10010512).

Assessment and marking:

1. A 4 hour written digital exam with books and notes of your own choice. Internet access is not allowed. Danish 7-point marking scale, external examiner. Exam aids allowed, not internet. A closer description of the exam rules will be posted under 'Course Information' on Blackboard. (5 ECTS). (10010502).

Reexamination in the same exam period or immediately thereafter. The mode of the re-examination may differ from the mode of the ordinary exam.

Expected working hours
The teaching method is based on three phase model.
Intro phase: 20 hours
Skills training phase: 30 hours, hereof:
 - Tutorials: 30 hours

Educational activities
Activities during the study phase: Work on project.Educational form

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.