BMB503: Fundamental Biochemistry (5 ECTS)

STADS: 01002501

Level
Bachelor course

Teaching period
The course is offered in the autumn semester.
Second quarter.

Teacher responsible
Email: m.miller@bmb.sdu.dk
Email: sand@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 16-18 U55 48
Common I Wednesday 16-18 U55 46
Common I Wednesday 08-10 U55 47-51
Common I Thursday 14-16 U55 45,47,49-50
Common I Friday 08-10 U55 46
S1 TE Monday 14-16 U37 49-51
S1 TL Wednesday 14-18 48-49
S1 TE Thursday 14-16 U37 48
S1 TE Friday 12-14 U9 46-47
S2 TE Monday 08-10 U17 46
S2 TL Monday 14-18 48-49
S2 TE Thursday 12-14 U49b 47-51
S3 TE Tuesday 12-14 U49b 46-51
S3 TL Friday 13-17 48-49
S4 TE Monday 12-14 U9 46-51
S4 TL Thursday 08-12 48-49
S5 TE Tuesday 14-16 U17 46-51
S5 TL Tuesday 08-12 48-49
S6 TL Monday 08-12 48-49
S6 TE Tuesday 10-12 U49b 46-48
S6 TE Tuesday 10-12 U26 49
S6 TE Tuesday 10-12 U48 50
S6 TE Tuesday 10-12 U49c 51
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Prerequisites:
None

Academic preconditions:
Students must have passed BB501 Biology - from Molecule to Ecosystem or BB508 and are expected to be familiar with the contents of BMB501 Biomolecular chemistry and BMB502 Enzymes and Membranes.

Course introduction
The course will give an introduction to the structure and function of eukaryotic cells at the molecular level. Biochemical processes in animal and plant cells will be presented with a special focus on metabolic pathways in mammalian cells and their regulation.

Qualifications
Students will:
• understand the general chemical basis of cellular processes and the principles for their regulation
• obtain basal experimental skills in Biochemistry
• collect data from practical experiments and analyze and interpreted the results from their theoretical background
• be able to write a report based on own observations and interpretations
• obtain a foundation for advanced courses on experimental-biological disciplines


Expected learning outcome


Subject overview
1. General principles for regulation
2. Metabolism: basic terms and principles
3. Glycolysis and Gluconeogenesis
4. The Citric Acid Cycle
5. Oxidative Phosphorylation
6. Glycogen Metabolisme
7. Metabolism of lipids including fatty acid biosynthesis and degradation
8. The Photosynthetic Light Reactions and mechanisms of CO2 fixation
9. The Integration of Metabolism

In addition a guest lecture will present a cutting edge lecture within a selected topic. Regulatory enzymes and oxidative phosphorylation will be the subject of 2 laboratory exercises.

Literature
  • Berg, Tymoczko & Stryer : Biochemistry, 6th edition, Freeman, 2006.


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
a) 4 hour written open-book examination. External examiner with grades according to the Danish 7-point scale.
b) Laboratory reports of the practicals are evaluated pass/fail by the instructor. Tha laboratory reports account for 1 ECTS.

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (24 timer), eksaminatorier (12 timer) og laboratorieøvelser (8 timer).
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.