BMB505: Metabolic regulation (10 ECTS)
        
        
		STADS: 1000501		
		
		
		
		
		
Level
		Bachelor course		
		
		
		
Teaching period
		The course is offered in the spring semester.		
3rd and 4th quarter.		
		
		
		
Teacher responsible
		 Email: nils.f@bmb.sdu.dk
Timetable
 Email: nils.f@bmb.sdu.dk
Timetable
		
				
		 
		  | Group | Type | Day | Time | Classroom | Weeks | Comment | 
		 
  | Common | I | Monday | 12-14 | U46 | 05 |  | 
 
  | Common | I | Monday | 12-14 | U37 | 06-11, 14, 16-21 |  | 
 
  | Common |  | Monday | 16-18 | U37 | 18(kollokvie) |  | 
 
  | Common |  | Tuesday | 10-12 | U44 | 22(kollokvie) |  | 
 
  | Common |  | Friday | 08-10 | U37 | 15-17(kollokvie) |  | 
 
  | Common |  | Friday | 08-10 | U37 | 19-21(kollokvie) |  | 
 
  | S1 | TL | Tuesday | 12-17 |  | 08-09 |  | 
 
  | S1 | TE | Wednesday | 08-10 | U37 | 06-11, 15-20 |  | 
 
  | S1 | TE | Friday | 13-15 | U20 | 21 |  | 
 
  | S2 | TE | Thursday | 14-16 | U37 | 06-11, 15-19, 21-22 |  | 
 
  | S2 | TL | Thursday | 10-15 |  | 08 |  | 
 
  | S2 | TL | Friday | 08-13 |  | 09 |  | 
		
		 
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Prerequisites:
None
Academic preconditions:
Passed ”BMB502, Enzymes and membranes”. BMB503, Knowledge of BMB503 Fundamental biochemistry. 
) is a prerequisite to follow the final 5 ECTS points (4th quarter).
	
Course introductionThe course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.  
QualificationsThe students will: 
• get detailed an understanding of cellular processes and the regulation on a molecular level 
• understand the background for the development of various metabolic diseases 
• be able to collect, form, understand, and interpret results and hence understand the theoretical background • be able to give a written presentation of own observations and interpretations 
• be able to orally present review articles
Expected learning outcomeSubject overview1. Regulation of glycolysis/gluconeogenesis/TCA 
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation 
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism 
7. Synthesis and degradation of nucleotides
8. Signal transduction 
9. Regulation of metabolism incl. glucose-fatty acid cycle 
10. Integration of metabolism
11. Glucocorticoids/steroid hormone receptors 
12. Ca++-signalling
13. Metabolic diseases 
The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.
	
	
LiteratureThere isn't any litterature for the course at the moment.	
	
		
Syllabus
	See syllabus.	
	
Website
This course uses  
e-learn (blackboard).
Prerequisites for participating in the exam
None
Assessment and marking:
Number of evaluations: 2. 
Written exam. Eksternal censorship. 13-scale.
Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.
Note: Pass of practical exercise/obligatory assignment for the first 5 ECTS points (3rd quarter) is a prerequisite to follow the final 5 ECTS points (4th quarter).
Expected working hours
The teaching method is based on three phase model.
Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer). 
Educational activities
Language
No recorded information about the language used in the course.
Course enrollment
See deadline of enrolment.
Tuition fees for single courses
See fees for single courses.