BMB505: Metabolic regulation (10 ECTS)

STADS: 1000501

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 12-14 U46 05
Common I Monday 12-14 U37 06-11, 14, 16-21
Common Monday 16-18 U37 18(kollokvie)
Common Tuesday 10-12 U44 22(kollokvie)
Common Friday 08-10 U37 15-17(kollokvie)
Common Friday 08-10 U37 19-21(kollokvie)
S1 TL Tuesday 12-17 08-09
S1 TE Wednesday 08-10 U37 06-11, 15-20
S1 TE Friday 13-15 U20 21
S2 TE Thursday 14-16 U37 06-11, 15-19, 21-22
S2 TL Thursday 10-15 08
S2 TL Friday 08-13 09
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Prerequisites:
None

Academic preconditions:
Passed ”BMB502, Enzymes and membranes”. BMB503, Knowledge of BMB503 Fundamental biochemistry.
) is a prerequisite to follow the final 5 ECTS points (4th quarter).

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Qualifications
The students will:
• get detailed an understanding of cellular processes and the regulation on a molecular level
• understand the background for the development of various metabolic diseases
• be able to collect, form, understand, and interpret results and hence understand the theoretical background • be able to give a written presentation of own observations and interpretations
• be able to orally present review articles

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Synthesis and degradation of nucleotides
8. Signal transduction
9. Regulation of metabolism incl. glucose-fatty acid cycle
10. Integration of metabolism
11. Glucocorticoids/steroid hormone receptors
12. Ca++-signalling
13. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature
There isn't any litterature for the course at the moment.

Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

Written exam. Eksternal censorship. 13-scale.

Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.

Note: Pass of practical exercise/obligatory assignment for the first 5 ECTS points (3rd quarter) is a prerequisite to follow the final 5 ECTS points (4th quarter).

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer).
Educational activities

Language
No recorded information about the language used in the course.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.