BMB505: Metabolic regulation (10 ECTS)

STADS: 01000501

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
sand@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 12-14 U26 15-20
Common I Tuesday 08-10 U55 19
Common I Tuesday 13-15 U26 22
Common I Thursday 08-10 U110 05-09, 11, 15-17, 19-21
Common I Friday 08-10 U9 18-19
Common I Saturday 10-12 U20 10
S1 TL Thursday 13-18 BMB 10-11
S1 TE Friday 12-14 U9 05-11
S1 TE Friday 12-14 U17 15, 17-21
S2 TL Monday 09-14 BMB 10-11
S2 TE Wednesday 14-16 U14 05-06,15-21
S2 TE Thursday 10-12 U49e 07-09,11
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Revison of timetable:
: Forelæsning tirsdag uge 22 rykket en time frem.
: E-timer hold S2 flyttet uge 07-11.
: Lab.øvelser ændret fra uge 09-10 TIL uge 10-11.

Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Signal transduction
8. Regulation of metabolism incl. glucose-fatty acid cycle
9. Integration of metabolism
10. Glucocorticoids/steroid hormone receptors
11. Ca++-signalling
12. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature
  • Stryer: Biochemistry, 6. edt.


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

Written exam. Eksternal censorship. 7-scale.

Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.

Note: Pass of practical exercise/obligatory assignment for the first 5 ECTS points (3rd quarter) is a prerequisite to follow the final 5 ECTS points (4th quarter).

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer).
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.