BMB505: Metabolic regulation (10 ECTS)

STADS: 01000501

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
sand@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 10-12 U140 15,17
Common I Monday 10-12 U9 19-22
Common I Wednesday 08-10 U140 06-12,18-22
Common I Thursday 08-10 U49 18-20
Common I Thursday 08-10 BMB seminarrum 23
Common I Friday 10-12 U26 22
S1 TE Monday 14-16 U20 07-12
S1 TE Monday 14-16 U14 17-22
S1 TL Tuesday 12-17 BMB 10
S1 TL Tuesday 12-17 U131 11
S1 TE Tuesday 08-10 U14 16
S2 TE Tuesday 14-16 U14 07-12,16-22
S2 TL Wednesday 12-17 BMB 10
S2 TL Wednesday 12-17 U70 11
S3 TL Monday 12-17 BMB 10
S3 TL Monday 12-17 U17 11
S3 TE Wednesday 14-16 U26 07-12
S3 TE Wednesday 14-16 U14 16-22
S4 TL Thursday 12-17 BMB 10
S4 TL Thursday 12-17 U24 11
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Revison of timetable:
: Erstatningsforelæsning torsdag uge 23 kl. 08-10.
: Ændrede lokaler for Kollokvier.

Comment:
Yderligere undervisere: Daniel Wüstner, adjunkt.

Forelæsningstimerne mandag uge 19-22 samt torsdag 18-20,22 er Kollokvier.

Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Signal transduction
8. Regulation of metabolism incl. glucose-fatty acid cycle
9. Integration of metabolism
10. Ca++-signalling
11. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature

  • Stryer: Biochemistry, 6. edt.
  • Frayn, Keith N: Metabolic regulation – A Human Perspective.


Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

Written exam. Eksternal censorship. 7-scale.

Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.

Note: Pass of practical exercise/obligatory assignment for the first 5 ECTS points (3rd quarter) is a prerequisite to follow the final 5 ECTS points (4th quarter).

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer).
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.