BMB505: Metabolic regulation (10 ECTS)

STADS: 01000501

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
sand@bmb.sdu.dk
wuestner@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 08-10 U140 05-11
Common Wednesday 14-16 U26 17-21
Common I Thursday 10-12 U55 15-18, 20-21
Common Friday 10-12 U53 18-21
S1 TL Tuesday 12-17 BMB´s øvelseslokale 08-09
S1 TE Thursday 14-16 U144 05-11, 15-16,18, 20-21
S1 TE Thursday 13-15 U48a 17
S2 TE Tuesday 14-16 U144 05-11, 16-20
S2 TE Tuesday 14-16 U143 21
S2 TL Thursday 12-17 BMB´s øvelseslokale 08-09
S3 TL Monday 12-17 BMB´s øvelseslokale 09
S3 TE Friday 08-10 U28 05-11, 15-16, 18-21
S3 TL Friday 12-17 BMB´s øvelseslokale 08
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Revison of timetable:
: S1 rykket en time frem d.29 april efter ønske.

Comment:
K onsdag og fredag står for kollokvier.

Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Signal transduction
8. Regulation of metabolism incl. glucose-fatty acid cycle
9. Integration of metabolism
10. Ca++-signalling
11. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature
  • Stryer : Biochemistry, 6. edt. J. M. Berg, J.L. Tymoczko og L. Stryer.
  • Lodish et al.: Molecular Cell Biology, Molecular Cell Biology, 6th edition (2007).
  • Frayn, Keith N: Metabolic regulation – A Human Perspective. , 2. edt.
  • Øvelsesvejledning.


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

Written exam. Eksternal censorship. 7-scale.

Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.

Note: Pass of practical exercise/obligatory assignment for the first 5 ECTS points (3rd quarter) is a prerequisite to follow the final 5 ECTS points (4th quarter).

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer).
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.