BMB505: Metabolic regulation (10 ECTS)

STADS: 01000501

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
sand@bmb.sdu.dk
wuestner@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 08-10 U140 05-11
Common Wednesday 14-16 U26 17-21
Common I Thursday 10-12 U55 15-18, 20-21
Common Friday 10-12 U53 18-21
S1 TL Tuesday 12-17 BMB´s øvelseslokale 08-09
S1 TE Thursday 14-16 U144 05-11, 15-16,18, 20-21
S1 TE Thursday 13-15 U48a 17
S2 TE Tuesday 14-16 U144 05-11, 16-20
S2 TE Tuesday 14-16 U143 21
S2 TL Thursday 12-17 BMB´s øvelseslokale 08-09
S3 TL Monday 12-17 BMB´s øvelseslokale 09
S3 TE Friday 08-10 U28 05-11, 15-16, 18-21
S3 TL Friday 12-17 BMB´s øvelseslokale 08
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Revison of timetable:
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Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Signal transduction
8. Regulation of metabolism incl. glucose-fatty acid cycle
9. Integration of metabolism
10. Ca++-signalling
11. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature
  • Stryer : Biochemistry, 6. edt. J. M. Berg, J.L. Tymoczko og L. Stryer.
  • Lodish et al.: Molecular Cell Biology, Molecular Cell Biology, 6th edition (2007).
  • Frayn, Keith N: Metabolic regulation – A Human Perspective. , 2. edt.
  • Øvelsesvejledning.


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

Written exam. Eksternal censorship. 7-scale.

Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.

Note: Pass of practical exercise/obligatory assignment for the first 5 ECTS points (3rd quarter) is a prerequisite to follow the final 5 ECTS points (4th quarter).

Date of exam
The ordinary exam takes place on June 11, 2010
The re-examination takes place on January 14, 2011

Expected working hours
The teaching method is based on three phase model.

44 lectures hereof 16 as colloquiums. 10 hours practicals/assignments.
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.