BMB505: Metabolic regulation (10 ECTS)

STADS: 01006801

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
wuestner@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 12-14 U140 16
Common Monday 14-16 U140 18-19
Common I Tuesday 10-12 U55 05-11, 14-15,17-19
Common Tuesday 14-16 U1 18-19
Common I Tuesday 10-12 U1 21
Common Tuesday 14-16 U140 22
Common Wednesday 16-18 U20 17-19
Common Wednesday 14-16 U20 21
S1 TL Monday 12-17 BMB´s øvelseslokale 09-10
S1 TE Monday 14-16 U140 16
S1 TE Thursday 08-10 U144 06-11, 14-15,17-19
S2 TE Monday 14-16 U140 16
S2 TL Wednesday 12-17 BMB´s øvelseslokale 09-10
S2 TE Friday 10-12 U144 06-11, 14-15,17-19
S3 TL Friday 13-18 BMB´s øvelseslokale 09-10
Show entire timetable
Show personal time table for this course.

Revison of timetable:
: Kollokvier onsdag uge 21 kl. 14-16 i U20 tilføjet
: Hold S3E nedlagt efter ønske.

Comment:
Laboratorieøvelsen afholdes under 3. kvartal.

Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Signal transduction
8. Regulation of metabolism incl. glucose-fatty acid cycle
9. Integration of metabolism
10. Ca++-signalling
11. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature
  • Lehninger: Principles of Biochemistry, 5. udgave .
  • David L. Nelson and Michael M. Cox: Metabolic Regulation, a human perspective , 2. udgave K. Frayn .
  • Øvelsesvejledning.


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

a) Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.
b) Written exam. Eksternal censorship. 7-scale.



Note: Pass of practical exercise/obligatory assignment is a prerequisite to take the written exam (4th quarter).

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer).
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.