BMB505: Metabolic regulation (10 ECTS)
        
        
		STADS: 01006801		
		
		
		
		
		
Level
		Bachelor course		
		
		
		
Teaching period
		The course is offered in the spring semester.		
3rd and 4th quarter.		
		
		
		
Teacher responsible
		 Email: nils.f@bmb.sdu.dk
Additional teachers
 Email: nils.f@bmb.sdu.dk
Additional teachers

 wuestner@bmb.sdu.dk
Timetable
		
				
		 
		  | Group | Type | Day | Time | Classroom | Weeks | Comment | 
		 
  | Common | I | Monday | 12-14 | U140 | 16 |  | 
 
  | Common |  | Monday | 14-16 | U140 | 18-19 |  | 
 
  | Common | I | Tuesday | 10-12 | U55 | 05-11, 14-15,17-19 |  | 
 
  | Common |  | Tuesday | 14-16 | U1 | 18-19 |  | 
 
  | Common | I | Tuesday | 10-12 | U1 | 21 |  | 
 
  | Common |  | Tuesday | 14-16 | U140 | 22 |  | 
 
  | Common |  | Wednesday | 16-18 | U20 | 17-19 |  | 
 
  | Common |  | Wednesday | 14-16 | U20 | 21 |  | 
 
  | S1 | TL | Monday | 12-17 | BMB´s øvelseslokale | 09-10 |  | 
 
  | S1 | TE | Monday | 14-16 | U140 | 16 |  | 
 
  | S1 | TE | Thursday | 08-10 | U144 | 06-11, 14-15,17-19 |  | 
 
  | S2 | TE | Monday | 14-16 | U140 | 16 |  | 
 
  | S2 | TL | Wednesday | 12-17 | BMB´s øvelseslokale | 09-10 |  | 
 
  | S2 | TE | Friday | 10-12 | U144 | 06-11, 14-15,17-19 |  | 
 
  | S3 | TL | Friday | 13-18 | BMB´s øvelseslokale | 09-10 |  | 
		
		 
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Revison of timetable:
	: Kollokvier onsdag uge 21 kl. 14-16 i U20 tilføjet
: Hold S3E nedlagt efter ønske.	
	
Comment:
	Laboratorieøvelsen afholdes under 3. kvartal.	
	
Prerequisites:
None
Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .
	
Course introductionThe course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.  
Expected learning outcomeSubject overview1. Regulation of glycolysis/gluconeogenesis/TCA 
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation 
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism 
7. Signal transduction 
8. Regulation of metabolism incl. glucose-fatty acid cycle 
9. Integration of metabolism
10. Ca++-signalling
11. Metabolic diseases 
The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.
	
	
Literature- 
Lehninger: 
Principles of Biochemistry, 
5. udgave .
- 
David L. Nelson and Michael M. Cox: 
Metabolic Regulation, a human perspective , 
2. udgave K. Frayn .
- 
Øvelsesvejledning.
Syllabus
	See syllabus.	
	
Website
This course uses  
e-learn (blackboard).
Prerequisites for participating in the exam
None
Assessment and marking:
Number of evaluations: 2. 
a) Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.
b) Written exam. Eksternal censorship. 7-scale.
Note: Pass of practical exercise/obligatory assignment is a prerequisite to take the written exam (4th quarter).
Expected working hours
The teaching method is based on three phase model.
Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer). 
Educational activities
Language
This course is taught in Danish.
Course enrollment
See deadline of enrolment.
Tuition fees for single courses
See fees for single courses.