BMB505: Metabolic regulation (10 ECTS)

STADS: 01006801

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
wuestner@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 12-14 U140 16
Common Monday 14-16 U140 18-19
Common I Tuesday 10-12 U55 05-11, 14-15,17-19
Common Tuesday 14-16 U1 18-19
Common I Tuesday 10-12 U1 21
Common Tuesday 14-16 U140 22
Common Wednesday 16-18 U20 17-19
Common Wednesday 14-16 U20 21
S1 TL Monday 12-17 BMB´s øvelseslokale 09-10
S1 TE Monday 14-16 U140 16
S1 TE Thursday 08-10 U144 06-11, 14-15,17-19
S2 TE Monday 14-16 U140 16
S2 TL Wednesday 12-17 BMB´s øvelseslokale 09-10
S2 TE Friday 10-12 U144 06-11, 14-15,17-19
S3 TL Friday 13-18 BMB´s øvelseslokale 09-10
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Revison of timetable:
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Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview
1. Regulation of glycolysis/gluconeogenesis/TCA
2. Lipidabsorption, transport and lipoproteins
3. Fatty acid degradation
4. Fatty acid synthesis
5. Compleks lipidsynthesis
6. Amino acid metabolism
7. Signal transduction
8. Regulation of metabolism incl. glucose-fatty acid cycle
9. Integration of metabolism
10. Ca++-signalling
11. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.

Literature
  • Lehninger: Principles of Biochemistry, 5. udgave .
  • David L. Nelson and Michael M. Cox: Metabolic Regulation, a human perspective , 2. udgave K. Frayn .
  • Øvelsesvejledning.


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

a) Practicals/Obligatory assignment. Internal censorship by teachers. Passed/not passed.
b) Written exam. Eksternal censorship. 7-scale.



Note: Pass of practical exercise/obligatory assignment is a prerequisite to take the written exam (4th quarter).

Date of exam
The ordinary exam takes place on June 6, 2011
The re-examination takes place on January 2, 2012

Expected working hours
The teaching method is based on three phase model.

44 lectures hereof 16 as colloquiums. 10 hours practicals/assignments.
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.