BMB505: Metabolic regulation (10 ECTS)

STADS: 01007101

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
Email: nils.f@bmb.sdu.dk

Additional teachers
wuestner@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 08-10 U55 10
Common I Monday 08-10 U55 15-18
Common I Monday 10-12 Kollokvier i U140 17-20
Common I Monday 08-10 U46 19-20
Common I Monday 08-10 U55 22
Common I Wednesday 08-10 U140 05-07
Common I Wednesday 08-10 U140 08-11
Common I Wednesday 08-10 Kollokvier i U55 17-20
Common I Friday 08-10 U55 21
S1 TL Monday 14-19 BMB øvelseslab 09
S1 TL Monday 14-19 U53 10
S1 TE Thursday 14-16 U130 07-08,10-11,15-18
S1 TE Thursday 14-16 U28 09
S1 TE Thursday 08-10 U155 20
S1 TE Thursday 14-16 U44 21
S1 TE Friday 10-12 U15 07
S1 TE Friday 08-10 U155 19
S2 TE Monday 14-16 U151 06-08,10-11
S2 TE Monday 08-10 U151 09
S2 TE Monday 14-16 U156 15-18
S2 TE Monday 12-14 U157 20
S2 TL Wednesday 10-15 BMB øvelseslab 09
S2 TL Wednesday 10-15 U24 10
S2 TE Wednesday 10-12 U147 21
S2 TE Friday 12-14 U156 19
S3 TE Wednesday 14-16 U144 15-18
S3 TE Thursday 08-10 U49c 07
S3 TL Thursday 09-14 BMB øvelseslab 09
S3 TE Thursday 14-16 U28 09
S3 TL Thursday 09-14 U16 10
S3 TE Thursday 08-10 U155 20
S3 TE Thursday 14-16 U44 21
S3 TE Friday 08-10 U147 07
S3 TE Friday 12-14 U148 08,10-11
S3 TE Friday 08-10 U155 19
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Revison of timetable:
: S1 og S3 lagt sammen torsdag i uge 09 efter ønske.

Comment:
Laboratorieøvelsen afholdes under 3. kvartal.

Samlæses med BMB521

Prerequisites:
None

Academic preconditions:
BMB502 Enzymes and membranes must be attended. Knowledge of BMB503 Fundamental biochemistry is a prerequisite .

Course introduction
The course aims to give an understanding of metabolic pathways in mammalian cells and their regulation at a molecular level. Participants will gain insights into signal transduction pathways incl. hormones, growth factors, receptors, kinases, calcium and transcription factors.

Expected learning outcome


Subject overview

  1. Regulation of glycolysis/gluconeogenesis/TCA
  2. Lipidabsorption, transport and lipoproteins
  3. Fatty acid degradation
  4. Fatty acid synthesis
  5. Compleks lipidsynthesis
  6. Amino acid metabolism
  7. Signal transduction
  8. Regulation of metabolism incl. glucose-fatty acid cycle
  9. Integration of metabolism
  10. Ca++-signalling
  11. Metabolic diseases

The glucose-fatty acid cycle as well as integration of metabolism will be illustrated via a practical exercise/obligatory assignment.



Literature
  • David L. Nelson and Michael M. Cox: Lehninger Principles of Biochemistry, 5. Udgave.
  • K. Frayn: Metabolic Regulation, a human perspective, 2. Udgave.
  • Øvelsesvejledning.


Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 3.

a) Practicals/Obligatory assignment (3rd quarter). Internal censorship by teachers. Pass/fail (2 ECTS). The report is made by three students together. The report must be passed in order to take the final electronic exam.
b) Oral presentation and report (max 5 pages) that cover metabolic disease. Internal evaluation by teacher, pass/fail (2 ECTS). The presentation and report are made by 4-5 students together. The activity must be passed to take the final electronic exam.
c) Written take-home exam. Eksternal censorship, 7-point grading scale. The exam will be released via Black Board and the stuedent will get 4 hours to answer the questions and submit the answers via Black Board as a word or pdf file.

Re-examination after 2nd quarter. br> The mode of exam at the reexamination may differ from the mode of exam at the ordinary exam.

Expected working hours
The teaching method is based on three phase model.

Forelæsninger (44 timer hvoraf 16 afholdes som kollokvier), eksaminatorier (26 timer) og laboratorieøvelser (10 timer).
Educational activities

Language
This course is taught in Danish.

Remarks
It is expected that student participates actively in at least 80% of the collquiums.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.