BMB508: Advanced Molecular Biology (10 ECTS)

STADS: 01002901

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3rd and 4th quarter.

Teacher responsible
No responsible teachers found, contact the department if necessary

Timetable

Group	Type	Day	Time	Classroom	Weeks
Common	I	Monday	08-10	U140	06,08-10,17-19
Common	I	Tuesday	10-12	U20	06
Common	I	Tuesday	10-12	U140	08-10,17-19
Common	I	Thursday	12-13	U140	06,08-09,16-19
Common	I	Thursday	11-13	U140	07
S1	TE	Monday	10-12	U140	08-11
S1	TE	Monday	12-14	U26a	18-21
S1	TE	Wednesday	16-18	U26	10-11
S1	TE	Wednesday	10-12	U26a	18-21
S1	TL	Wednesday	14-19		21
S1	TE	Friday	10-12	U131	08
S1	TE	Friday	10-12	U28	09
S1	TL	Friday	12-17		21-22
S2	TE	Monday	12-14	U26a	08-09
S2	TE	Tuesday	08-10	U26a	18-21
S2	TL	Tuesday	14-19		21
S2	TL	Tuesday	08-13		22
S2	TE	Wednesday	10-12	U26a	10-11
S2	TL	Thursday	13-18		22
S2	TE	Friday	08-10	U26a	08-11,18,20-22
S3	TL	Monday	14-19		21
S3	TL	Tuesday	13-18		22
S3	TL	Thursday	08-13		22

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Revison of timetable:
: Aflyst forelæsning mandag uge 6 flyttet til torsdag uge 7!
: Lab hold S2 og S3 flyttet fra torsdag uge 21 til tirsdag uge 22.
: Forelæsninger flyttet fra uge 7 til uge 6 efter ønske.

Prerequisites:
None

Academic preconditions:
Passed BB501 Biology from molecule to ecosystem. Knowledge of the content of BMB504 Fundamental Molecular Biology.

Students who has passed BM114 cannot participate in this course.

Course introduction
The course represents a continuation of the course ”Fundamental Molekylær Biologi, and the aim is to provide a coherent understanding of the transmission and exchange of genetic information, to provide knowledge of the characteristics of biological processes at the molecular level in prokaryotes and eukaryotes, and how these processes differ between prokaryotes and eukaryotes. Examples comprising a diverse range organisms including man will be used to illustrate cellular functions and developmental processes.

Expected learning outcome

Subject overview
The course will cover the following topics:

1. Eukaryotic genome organization and replication
2. Methods for analysis of gene function, recombinant DNA technology, gene arrays, transgenic and knockout animals, ethical considerations
3. Regulation of transcription in eukaryotes
4. Posttranscriptional regulation, RNA modification, processing, splicing, catalytic RNA and nuclear-cytoplasmic transport
5. Translation of mRNA in eukaryote organisms. Protein localization and export
6. Control of gene activity via cellular signaling (signal transduction) and integration of celluæar signaling in the control of gene expression
7. Metabolic control at the molecular level
8. Control of the cell cycle in eukaryote organisms
9. Cancer at the molecular level, oncogenes, tumor suppressors, DNA damage and repair, signal transduction, hormones and receptors

Literature

Lodish et al.: Molecular Cell Biology: Molecular Cell Biology, 6th edition (2007)..

Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Number of evaluations: 2.

Approval by teacher of report on laboratory exercises. Written examination (4 hours) with no books, and marks according to the Danish 7 point grading system with external examinators.

Expected working hours
The teaching method is based on three phase model.

Undervisningen vil bestå af forelæsninger (40 timer), som suppleres med eksaminatorier (24 timer) og laboratorieøvelser (15 timer). Kommunikation mellem lærerne og de studerende med hensyn til forelæsningsnoter, opgaver m.m. vil foregå via SDU’s e-learning system.
Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.