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Dansk English

BMB508: Advanced Molecular Biology (10 ECTS)

STADS: 01009401

Level
Bachelor course

Teaching period
The course is offered in the spring semester.

Teacher responsible
Email: jens.andersen@bmb.sdu.dk

Additional teachers
bragea@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 10-12 U45 08,13,16
Common I Monday 08-10 U55 21
Common I Tuesday 12-14 U140 10
Common I Tuesday 13-15 U55 18,20
Common I Wednesday 08-10 U45 06
Common I Thursday 08-10 U55 15,17,19
Common I Friday 10-12 U55 06,08,10-13
H1 TE Tuesday 10-12 U24 07,10-11,13,16-17
H1 TE Tuesday 10-12 U31a 18-19
H1 TE Tuesday 12-14 U156 21
H1 TL Wednesday 12-17 Blue lab 10
H1 TE Wednesday 16-18 U156 12
H1 TE Thursday 08-10 U156 07,10
H1 TL Thursday 12-17 Blue lab 10
H1 TL Friday 12-17 Blue lab 10
H1 TE Friday 10-12 U156 20
H2 TE Monday 08-10 U48 07,10,18-19
H2 TL Wednesday 12-17 Blue lab 11
H2 TL Thursday 12-17 Blue lab 11
H2 TE Thursday 08-10 U156 21
H2 TE Friday 12-14 U154 07,12-13,16-17
H2 TE Friday 08-10 U153 10-11
H2 TL Friday 12-17 Blue lab 11
H2 TE Friday 12-14 U156 20
H3 TE Monday 12-14 U48 07,10
H3 TE Monday 15-17 U30 11-12,16-19
H3 TL Monday 08-13 Blue lab 12
H3 TE Wednesday 08-10 U154 07,10
H3 TL Thursday 13-18 Blue lab 12
H3 TE Thursday 12-14 U154 13
H3 TE Thursday 12-14 U155 21
H3 TL Friday 12-17 Blue lab 12
H3 TE Friday 14-16 U156 20
H4 TL Monday 09-14 Blue lab 14
H4 TL Tuesday 09-14 Blue lab 14
H4 TL Wednesday 09-14 Blue lab 14
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Comment:
Samlæses med BMB809

Prerequisites:
None

Academic preconditions:
BB501 Biology from molecule to ecosystem or FF503 must be passed. It is required that the content of the course BMB504 Fundamental Molecular Biology is known.



Course introduction
The course represents a continuation of the course ”Fundamental Molekylær Biologi, and the aim is to provide a coherent understanding of the transmission and exchange of genetic information, to provide knowledge of the characteristics of biological processes at the molecular level in prokaryotes and preferentially eukaryotes, and how these processes differ between prokaryotes and eukaryotes. Examples comprising a diverse range organisms including man will be used to illustrate cellular functions and developmental processes.

Expected learning outcome


Subject overview
The course will cover the following topics:

  1. Eukaryotic genome organization and replication
  2. Methods for analysis of gene function, recombinant DNA technology, gene arrays, transgenic and knockout animals, ethical considerations
  3. Regulation of transcription in eukaryotes
  4. Posttranscriptional regulation, RNA modification, processing, splicing, catalytic RNA and nuclear-cytoplasmic transport
  5. Translation of mRNA in eukaryote organisms. Protein localization and export
  6. Control of gene activity via cellular signaling (signal transduction) and integration of celluæar signaling in the control of gene expression
  7. Metabolic control at the molecular level
  8. Control of the cell cycle in eukaryote organisms
  9. Cancer at the molecular level, oncogenes, tumor suppressors, DNA damage and repair, signal transduction, hormones and receptors
Literature
  • Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter: Molecular Biology of the Cell, Edition:6th , ISBN:9780815344322 .


Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
  1. Approval by teacher of report on laboratory exercises. Pass/fail. 
  2. Approval of case study reports, pass/fail with internal evaluation be teacher.
  3. Written examination (4 hours) with no books, and marks according to the Danish 7 point grading system with external examinators.

Reexamination in the same exam period or immediately thereafter



Expected working hours
The teaching method is based on three phase model.
Intro phase: 40 hours
Skills training phase: 39 hours, hereof:
 - Tutorials: 24 hours
 - Laboratory exercises: 15 hours

Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.