BMB522: Molecular Biology and Human Genetic Disorders (5 ECTS)

STADS: 01002201

Level
Bachelor course

Teaching period
The course is offered in the autumn semester.

Teacher responsible
Email: bag@bmb.sdu.dk
Email: ogi@bmb.sdu.dk

Timetable
Show entire timetable
Show personal time table for this course.

Revison of timetable:
: Den aflyste time torsdag uge 51, afholdes fredag d. 17 januar kl. 12-14 i U67.
: Forelæsningerne i BMB522 om mandagen fra kl. 10-12 i ugerne 48-49, har følgende ændringer: Uger ændret fra 48-49 til 48 Lokale ændret fra til BMB`s seminarrum
: Forelæsningerne i BMB522 om mandagen fra kl. 08-10 i ugerne 38,40-41,43-49, har følgende ændringer: Uger ændret fra 38,40-41,43-49 til 38,40-41,43-47

Comment:
Den aflyste time torsdag uge 51, afholdes d. 17 januar kl. 12-14 i U67.

max antal studerende 30

Prerequisites:
None

Academic preconditions:
The content of BMB505 and BMB532 is assumed known.

Course introduction
To give students a thorough introduction into selected genetic diseases and the molecular changes involved in them. This part is accompanied by lectures on state-of-the-art methods currently used in cell biology, enabling the students to understand the methodological background for the exploration of the various diseases etiology.

Expected learning outcome


Subject overview
Part 1
General techniques in tissue culture, observations of live cells, biochemical/biophysical analyses of cells, - transfer of molecules into cells, labeling of proteins in intact cells, gene manipulation: transgenics

Part 2
Circadian genes- bipolar disorders,  neurodegenerative diseases I and II, Mitochondrial diseases, Phosphoinositide signaling disorders in human disease, Disorders of lipoprotein metabolism, Cancer 1: Hormone-regulation in breast and urogenital tumors, Cancer 2: Personalized medicine – the prospects of drug-targeting signaling pathways, Cancer 3: Tumor metastasis: mechanistic insights and clinical challenges

Literature

• Undervisningsnoter.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Written exam. External examiner. 7 point grading scale.

The reexamination is held as an oral exam. 7 point grading scale, internal examiner with the teacher

Expected working hours
The teaching method is based on three phase model.

Del 1: Forelæsninger 24 timer. Del 2 = 18 timers forelæsning og 7 eksaminatorietimer. De studerende skal give en mundtlig præsentation som forklarer de specifikke aspekter vedrørende de teknikker og sygdomme der undervises i.
Educational activities

Language
This course is taught in English.

Remarks
Part 1 is given in English. Part 2 is given in Danish or English, depending upon the participation of international students.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.