BMB527: Mechanisms of Eukaryotic Cell Signalling and Cell Differentiation (5 ECTS)

STADS: 01005601

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
3. quarter

Teacher responsible
Email: bab@bmb.sdu.dk

Additional teachers
ihk@bmb.sdu.dk
jens.andersen@bmb.sdu.dk

Timetable
There is no timetable available for the chosen semester.

Prerequisites:
None

Academic preconditions:
For SDU students: BM113 or BMB503 Fundamental Biochemistry & BMB505 Metabolic regulation must be passed

Course introduction
To give students a thorough introduction to signalling events which underlie eukaryote cell function and dysfunction. Mechanism by which extracellular signals are transmitted to cells and exert their effects will be discussed. Principles of stem cell differentiation involving various signalling networks will be disscussed as well. Participants will learn about the roles of signalling molecules such as hormones, receptors, kinases, and transcription factors. Participants will also gain experience in reading original research articles and in oral and written presentation of scientifc results.

Expected learning outcome


Subject overview
Principles of signalling networks
Growth factor signalling and its involvement in cancer
PI3K-signalling
Transforming growth factor beta (TGF-beta) signalling
Stem cell differentiation
Proteomics approahes to cell signalling and systems biology


Literature

• Harvey Lodish: Molecular Cell Biology, W.H. Freeman.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:


Expected working hours
The teaching method is based on three phase model.

Forelæsninger (12 timer), studenter præsentationer (8 timer) labaratorieøvelser (16 hours). Instruktor yder råd og vejledning ved rapportskrivning.
Educational activities

Language
This course is taught in English.

Remarks
Minimum 6 students are requrired to hold the course.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.