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BMB803: Molecular Microbiology (5 ECTS)

STADS: 01016901

Level
Master's level course

Teaching period
The course is offered in the autumn semester.

Teacher responsible
Email: srd@bmb.sdu.dk

Additional teachers
r.p.cox@bmb.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 14-16 U30 45
Common I Wednesday 10-12 U24 40
Common I Thursday 12-14 U146 36
H1 TE Monday 14-16 U154 43
H1 TE Tuesday 14-16 U146 37
H1 TE Tuesday 08-10 U11 39
H1 TE Tuesday 12-14 U155 41
H1 TE Tuesday 08-10 U156 44,46
H1 TE Tuesday 12-14 U154 47
H1 TE Tuesday 08-10 U24 48
H1 TE Wednesday 08-10 U11 37-38
H1 TE Wednesday 10-12 U24 41
H1 TE Thursday 12-14 U107 43
H1 TE Thursday 12-14 U30 44
H1 TE Thursday 14-16 U30 46
H1 TE Thursday 12-14 U145 47
H1 TE Thursday 10-12 U24 48
H1 TE Friday 14-16 U11 38-39
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Comment:
Studerende, der har taget BMB803 i 10 ECTS-version, kan ikke følge dette kursus.

Prerequisites:
None

Academic preconditions:
Students taking the course are expected to:
  • Have knowledge of basic microbiology, biochemistry and molecular biology at the level of a bachelor's degree in biological science
  • Be able to use Powerpoint or similar presentation software
  • Be sufficiently fluent in English to give oral presentations and write reports
 


Course introduction
The aim of the course is to enable the student to obtain a broader knowledge and understanding of molecular processes in bacteria through a discussion of mechanisms leading to resistance to antimicrobial compounds. The course will give students experience in reading and understanding the latest research literature and communicating current results and concepts.

The course builds on the knowledge acquired in introductory courses in biochemistry, molecular biology, and microbiology (BMB507 and   BMB508, or similar) and contributes to the academic basis for a final year Masters thesis on a microbiological topic and employment in biotechnological industry or the health sector. 

In relation to the competence profile of the degree it is the explicit focus of the course to:
  • give the competence to independently acquire new knowledge at the highest professional level and integrate new knowledge with previous experience
  • give skills to critically evaluate original research findings and  presentation of research both orally and in writing
  • give knowledge of theoretical and experimental methods used in investigations of bacteria using molecular and structural biology


Expected learning outcome
The learning objective of the course is that the student demonstrates the ability to:
  • describe the main types of antimicrobial compounds used in treating infectious disease and explain their mechanism of action
  • describe the different mechanisms leading to resistance
  • critically evaluate original research articles on resistance to antimicrobial compounds and present seminars in English 
Subject overview
The following main topics are contained in the course
  • Modern techniques used in molecular and structural biology
  • Major types of antibiotic and their mechanisms of action
  • Resistance against antibiotics 
  • Evolutionary theory applied to microbes as exemplified by the development of resistance to antibiotics
  • Antibiotics inhibiting ribosome function and mechanisms of resistance to these  
  • Structure and function of multidrug efflux pumps
 


Literature
There isn't any litterature for the course at the moment.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
  1. Satisfactory presentation of two research articles. Pass/fail, internal evaluation by instructor. Prerequisite examination is a prerequisite for participation in exam element a). (01016912).
Assessment and marking:
  1. Final report with oral examination. Internal marking, 7-mark scale. (5 ECTS). (01016902). A closer description of the exam rules will be posted under 'Course Information' on Blackboard.


Expected working hours
The teaching method is based on three phase model.
Intro phase: 8 hours
Skills training phase: 36 hours, hereof:
 - Tutorials: 36 hours

Educational activities
  • Reading research articles and preparing presentations in Powerpoint or similar
  • Reading articles to be presented by other students in preparation for active participation in discussion
  • Writing the final report
Educational form
The introductory phase comprises 12 hours of lecture where the main course themes are introduced. The skills training phase contains 32 hours of scheduled student presentations using Powerpoint or similar with subsequent discussion

Language
This course is taught in English.

Remarks
This course is a prerequisite for the associated laboratory course BMB827 Molecular Microbiology Laboratory.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.