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FA805: Experimental methods in pharmaceutics & biopharmaceutics (15 ECTS)

STADS: 03000501

Level
Master's level course

Teaching period
The course is offered in the spring semester.

Teacher responsible

Email: mmb@sdu.dk

Timetable

Group	Type	Day	Time	Classroom	Weeks	Comment
Common	I	Monday	09-12	U142	17
Common	I	Tuesday	09-12	U145	17
Common	I	Tuesday	09-11	U143	18
Common	I	Wednesday	09-12	U142	16
Common	I	Wednesday	10-12	U145	17
Common	I	Wednesday	09-14	U155	22	Eksaminatorietimer til mundtlig fremlæggelse
Common	I	Thursday	10-12	U48	16
Common	I	Thursday	09-12	U143	17
Common	I	Friday	08-11	U142	16
Common	I	Friday	09-12	U143	17
H2	TE	Monday	13-15	U26	17
H2	TE	Tuesday	12-14	U143	18
H2	TE	Wednesday	13-15	U145	17
H2	TE	Wednesday	10-12	U143	18
H2	TE	Friday	12-14	U142	16
H2	TE	Friday	13-15	U143	17

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Prerequisites:
None

Academic preconditions:

Students taking the course are expected to:

Have knowledge corresponding to bachelor level in pharmacy
The main contents of the course “Drug Transport & Drug Delivery Systems” or similar are expected to be known

Course introduction

The students should after completing the course possess well-founded knowledge about the most important experimental methods in (biop)harmaceutics, as well as skills regarding the methods used. The students should know the methods fundamental strengths and weaknesses (limitations), which is important in relation to pharmaceutical research.

The course builds on the knowledge acquired in the courses Fa501, Fa502, Fa503 and Fa504, as well as the master course ”Drug transport and drug delivery systems”and gives an academic basis for performing a master project within biopharmaceutics or a research project, that is part of the degree.

In relation to the competence profile of the degree it is the explicit focus of the course to:

Provide knowledge about and propagate understanding for the importance of dosage form design for drug absorption
Build skills in the appropriate use of experimental methods, including design of experiments within formulation design and process-development
Provide competences within development, production and quality assurance of pharmaceutical preparations

Expected learning outcome

The learning objective of the course is that the student demonstrates the ability to:

select and discuss pro´s and con´s of a concept or a technology appropriate for solving a task within research, development, production or quality assurance of pharmaceutical products
handle/use equipment typically available in pahramceutical research- and development laboratories
document correct use of methods with a focus on assuring reliable and reproducible results in accordance with current rules and regulations
report and convey research findings, both in writing and orally

Subject overview

The following main topics are contained in the course:

Self-contained planning, performing and reporting of laboratory experiments with (bio)pharmaceutics
Appropriate handling of chemicals and equipment during experimental work at pharmaceutical research-/development-laboratories
Literature research in pharmaceutical, life-science and medical databases
Evaluation of primary and secondary literature
Planning and documentation of experimental lab work incl design of experiments and evaluation of results by statistical means
Writing of scientific reports and manuscripts for journal articles
Oral and poster-presentation of experimental findings
The content of the course will vary depending on the needs of participants and availability of teachers/supervisors. It is natural to take up methods, which fit eith the participants master-projects, such as e.g. drug solid state, solubility, dissolution rate, permeability across biological and biomimetic barriers, liposomes as drug carriers, nanoparticles, bio-adhesion; particle size analysis; the role of drug transporters on drug absorption, distribution, metabolism and excretion (ADME)

Literature
There isn't any litterature for the course at the moment.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:

Expected working hours
The teaching method is based on three phase model.
Intro phase: 30 hours
Skills training phase: 25 hours, hereof:
- Tutorials: 17 hours
- Laboratory exercises: 8 hours

Educational activities
The final two/third of the course consist of compulsory project work under the guidance of supervisor (typically the supervisor of the master-project), where the produce methodological projects-reports, which form the basis for evaluation.Educational form

Study phase / project work: as deemed relevant with respect to the envisaged master project.

Activities envisaged for the study phase / project work

Consolidation and follow-up of lectures, seminars and lab-exercises
Self-contained application of acquired knowledge and skills to individual establishment, testing and application of other experimental techniques (under supervision)

Language
This course is taught in Danish or English, depending on the lecturer.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.