FY518: Nanobioscience Methods (5 ECTS)

STADS: 07001901

Level
Bachelor course

Teaching period
The course is offered in the autumn semester.
2. quarter.

Teacher responsible
Email: adam@memphys.sdu.dk

Timetable
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Revison of timetable:
F j, Y: Timetable has changed

Prerequisites:
None

Academic preconditions:
None

Course introduction
Introduction to important experimental techniques for preparation and characterization of nanobio systems. The course consists of lectures, problems, demonstrations and simple hands-on experiments.

Expected learning outcome
At the end of the course the student must be able to:

1. Describe the principles of concrete nanobioscience techniques covered in the course.
2. Evaluate whether or not a given characterization technique is suitable for a specific purpose within nanobioscience.
3. Design an experiment and choose the relevant methods to carry it out.
4. Write a simple Labview program to interface with experimental hardware

Subject overview
• An introduction to nanoscience laboratory experiments. Use of SDU workshop facilities including the manufacturing custom components for use in experimental setups. Technical drawings. Basic and advanced use of optical microscopes and optical detection systems including CCD cameras. Resolution in optical microscopy. Visualization of nanostructures smaller than the resolution limit. Single molecule visualization. Contrast methods in optical microscopy.
• The use of fluorescence as a contrast method. Examples include the incapsulation of fluorophores in liposomes, and their release from liposomes. Fluorescence spectroscopy. Fluorescence microscopy
• High resolution scanning probe microscopy including Atomic Force Microscopy (AFM). Practical demonstration of AFM
• Preparation of biologically functionalized surfaces including supported lipid bilayers and monolayers. Characterization of biomolecular surfaces with AFM.
• Experimental introduction to synthesis of nanoparticles. Hands-on synthesis of quantum dots.
• Introduction to electron spin resonance (ESR).
• Introduction to Labview, instrument control, data acquisition and data analysis.
• Basic clean room technology and microfabrication. Basic lithographic techniques. Patterning and Etching. Microcontact printing and soft lithography. Excursion to the SDU cleanroom at ALSION (Sønderborg)

Literature

• Udleverede noter, opgaver og slides.

Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Oral Exam. passed/not passed. Internal examiner. The students prepare individually a written report (10 pages) focusing on a specific characterization technique. The report should also contain examples from the literature describing applications of the technique. At the exam the student gives a 15 min. oral presentation of the report followed by a 15 min examination.

Date of exam
The ordinary exam takes place on January 21, 2009
The re-examination takes place on June 9, 2009

Expected working hours
The teaching method is based on three phase model.

Lectures: 15 hours.
Tutorials: 15 hours.
Laboratory exercises: 10 hours.
Excursion: 10 hours.
Educational activities

Language
No recorded information about the language used in the course.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.