FY518: Nanobioscience Methods (5 ECTS)

STADS: 07001901

Level
Bachelor course

Teaching period
The course is offered in the autumn semester.
2nd quarter.

Teacher responsible
Email: adam@memphys.sdu.dk

Additional teachers
kloesgen@ifk.sdu.dk

Timetable
Show entire timetable
Show personal time table for this course.

Comment:
Obligatorisk kursus på Nanobioscience studieretningen. Kører i forlængelse af FY514 Nanobioscience-systemer. Afvikles med 2x2 timers klasseundervisning per uge samt demonstrationsøvelser og afsluttende individuel projektskrivning. Kan tages som valgfrit kursus af andre interesserede fysik- eller kemistuderende. Kontakt Adam Cohen Simonsen for yderligere spørgsmål.

Prerequisites:
None

Academic preconditions:
Science year passed.

Course introduction
Introduction to important experimental techniques for preparation and characterization of nanobio systems. The course consists of lectures, problems, demonstrations and simple hands-on experiments.

Expected learning outcome
At the end of the course the student must be able to:
1. Describe the principles of concrete nanobioscience techniques covered in the course.
2. Evaluate whether or not a given characterization technique is suitable for a specific purpose within nanobioscience.
3. Design an experiment and choose the relevant methods to carry it out.
4. Write a simple Labview program to interface with experimental hardware

Subject overview
• Basic and advanced use of optical microscopes and optical detection systems including CCD cameras. Resolution in optical microscopy. Visualization of nanostructures smaller than the resolution limit. Single molecule visualization. Contrast methods in optical microscopy.
• The use of fluorescence as a contrast method. Examples include the incapsulation of fluorophores in liposomes, and their release from liposomes. Fluorescence spectroscopy. Fluorescence microscopy
• High resolution scanning probe microscopy including Atomic Force Microscopy (AFM). Practical demonstration of AFM
• Preparation of biologically functionalized surfaces including supported lipid bilayers and monolayers. Characterization of biomolecular surfaces with AFM
• Experimental introduction to synthesis of nanoparticles. Hands-on synthesis of quantum dots.
• Introduction to Labview, instrument control, data acquisition and data analysis.
• Individual project work based on literature study of an experimental characterization technique for preparing or characterizing nanostructures.

Literature

Udleverede noter, opgaver og slides

Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Oral examination taking its atarting point in a written report (10 pages) which focuses on a specific technique or method of characterization. Furthermore the report must describe one or more esamples from the litterature on the uses of the described method. The student will give a 15 minute oral presentation based on the report followed by questioning.
Graded with pass/fail and internal marking.

Re-examination after 4th quarter.

Expected working hours
The teaching method is based on three phase model.

Forelæsninger, antal timer 15.
Eksaminatorietimer/opgaveregning, antal timer 15.
Laboratorieøvelser, antal timer 10.
Ekskursion, antal timer 10.
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.