KE504: Analytical Spectroscopy (5 ECTS)

STADS: 10002101

Level
Bachelor course

Teaching period
The course begins in the autumn semester and continues in the spring semester.
1st and 3rd quarter.

Teacher responsible

Email: pcs@ifk.sdu.dk

Timetable

Group	Type	Day	Time	Classroom	Weeks
Common	I	Monday	09-10	U55	35
Common	I	Monday	10-11	U56	36
Common	I	Monday	09-10	U49	37-38
Common	I	Tuesday	10-11	U140	35-38
Common	I	Wednesday	10-11	U140	35-37
Common	I	Wednesday	10-11	U55	38
Common	I	Friday	10-11	U49	35-38
S1	TE	Monday	12-13	U90	36
S1	TE	Monday	12-13	U14	37-41
S1	TL	Tuesday	11-14	Spektroskopilokalet	36-40
S1	TE	Thursday	12-13	U7	35
S1	TE	Thursday	12-13	U14	36-39
S1	TL	Friday	12-14	Spektroskopilokalet	36-39
S1	TL	Friday	08-10	Spektroskopilokalet	40
S2	TL	Monday	14-16	Spektroskopilokalet	36-40
S2	TE	Monday	11-12	U90	36
S2	TE	Monday	11-12	U14	37-41
S2	TE	Thursday	08-09	U7	35
S2	TL	Thursday	13-16	Spektroskopilokalet	36-40
S2	TE	Thursday	08-09	U14	36-39
S3	TE	Monday	13-14	U82b	36-41
S3	TL	Wednesday	14-17	Spektroskopilokalet	36-40
S3	TE	Thursday	09-10	U17	35-38
S3	TL	Friday	15-17	Spektroskopilokalet	36-38
S3	TL	Friday	10-12	Spektroskopilokalet	39-40
S3	TE	Friday	14-15	U17	39

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Revison of timetable:
: Hold S3 er forbeholdt studerende der læser Lægemiddelvidenskab med tilvalg i farmaci.

Prerequisites:
None

Academic preconditions:
None.

Course introduction
The aim of the course is to provide the students with information on molecular spectroscopy and its application for analytical purposes.

Expected learning outcome
After the course, the students are expected to be able to:

• indentify functional groups and identify which form of spectroscopy being able to detection of a given group
• interpret experimental MS, IR and NMR spectra for the indeintification of small, unknown organic molecules by any of the spectroscopical methods or a combination of methods
• combine and value larger amounts of spectroscopic data from the different technices for the purpose of structure determination
• discuss the validity of a suggested molecular structure based on experimental spectra
• solve combined problems on analytical spectroscopy

Subject overview
I. Mass spectrometry (MS):

Introduction to MS

Determination of molecular formula

Fragmentation patterns

Application of MS for identification

II. Infrared spectroscopy (IR):

Introduction to IR spectroscopy

Application of IR spectra for identification

III. Magnetic resonance spectroscopy (NMR):

Introduction to NMR spectroscopy

Chemical shift
H-NMR: Spin-spin coupling, Application of 1H-NMR for identification
C-NMR: Application of 13C-NMR for identification

Advanced NMR techniques: DEPT sequence, two-dimensional NMR spectroscopy (COSY spectra, HETCOR technique), application of NMR for identification.

Literature

• D.L. Pavia, G.M. Lampman, G.S. Kriz og J.R. Vyvyan: Introduction to Spectroscopy, 4. udgave, Brooks/Cole, 2009.
• Analytisk Spektroskopi - Opgaver og øvelsesvejledning, 2004.

Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
(1) Obligatory assignments and reports, passed/not passed, internal evaluation by lecturer.
This part is worth 1 ECTS point.

(2) A 4 hour written exam graded according to the Danish 7-point scale and with external evaluation.
This part is worth 4 ECTS points.

Reexamination after 4th quarter.

Expected working hours
The teaching method is based on three phase model.

15 forelæsninger og 11 regneøvelser, obligatoriske laboratorieøvelser (10*2½=25 timer).
Educational activities

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.