KE505: Organic chemistry (10 ECTS)

STADS: 10008801

Level
Bachelor course

Teaching period
The course is offered in the spring semester.

Teacher responsible
Email: pouln@sdu.dk

Timetable
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Prerequisites:
None

Academic preconditions:
Students from the Faculty of Science: KE501 Fundamental Chemistry or FF503 og FF504 must be passed.
Students from the Faculty of Engineering: K-501/KC-501 Fundamental Chemistry must be passed.

Course introduction
The aim of the course is to go through the organic chemistry in detail and systematically. Hereby the course provides a fundamental knowledge for advanced chemistry and pharmacy courses and completion of a bachelor project within organic chemistry and medicinal chemistry.

Expected learning outcome
When the course is finished, the student is expected to be able to:

• describe the structures of complicated organic molecules, i.e. to identify and name functional groups and structural elements and describe their stereochemical properties
• apply the knowledge of organic reaction and reagents to write down and plan syntheses in one or more synthetic steps and argue for the formation of by-products
• write down and use reaction mechanisms
• explain and analyze the stereochemical consequences of various reactions
• carry out selected operations in an organic synthetic laboratory
• prepare selected organic compounds

Subject overview
The following topics will be treated and discussed:

1. Stereochemistry
2. Alkanes and their reactions
3. Alkenes and their reactions
4. Alkynes and their reactions
5. Delocalization and resonance
6. Reactions of dienes
7. Substitution reactions
8. Elimination reaktions
9. Reaktions of alcohols, ethers og epoxides
10. Aromaticity og benzene reaktions
11. Reaktions of substitute benzenes
12. Reactions of carbonyl compounds
13. Oxidation reactions and reduction reactions
14. Amines / heterocyclic compounds
15. Correct behaviour in an organic synthetic laboratory
16. Basic operations in an organic synthetic laboratory

Literature

• Paula Y. Bruice: Organic Chemistry , (Adapted from 7th Edition by Poul Nielsen).
• Jan O. Jeppesen/Poul Nielsen: Øvelsesvejledning til KE505, 2015. (Publiceres via Blackboard) .
• INSTITUT FOR FYSIK, KEMI og FARMACI: Organisk Kemi – KE505, Eksamensopgaver 2003–2014. (Publiceres via Blackboard) .

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:

1. Reports on lab exercises which are evaluated collectively, pass/fail, internal censorship by lecturer. The candidate must have passed the reports to be able to participate in the written examination. (10008812)
2. Delivery of acceptable answers to 11 out of 14 mandatory assignments. The assignments are evaluated colletively, pass/fail, internal censorship by lecturer. The candidate must have passed the assignments to be able to participate in the written examination. (10008822)
3. A 5 hours written examination, graded according to the 7-point scale, external censorship. (10008802)

Reexamination in the same exam period or immediately thereafter. The examination type at reexamination may differ from the one at the ordinary examination.

Expected working hours
The teaching method is based on three phase model.
Intro phase: 28 hours
Skills training phase: 74 hours, hereof:
 - Tutorials: 44 hours
 - Laboratory exercises: 30 hours

Educational activities Study phase: 148 hours

Language
This course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.