KE506: Synthesis (5 ECTS)

STADS: 10009801

Level
Bachelor course

Teaching period
The course is offered in the autumn semester.

Teacher responsible
Email: joj@sdu.dk

Timetable
Show entire timetable
Show personal time table for this course.

Prerequisites:
None

Academic preconditions:
KE505 Organic chemistry is presupposed known; KE521 Chemistry of the elements (or KE528 Introductory inorganic chemistry) and KE523 Physical Chemistry A must be attended, KE504 Analytical spectroscopy is recommended.

TEK-students: Bachelor in Technological Science (Chemistry) or similar, or admitted to a Master of Science in Engineering - Chemistry

Course introduction
The aim of the course is to give the students a detailed knowledge about common operations used in a synthetic laboratory. Thus, the objective of the course is to provide the students with fundamental knowledge that forms the basis for the completion of a bachelor project within synthetic chemistry.

Expected learning outcome
When the course is completed the student is expected to:

• relate theoretical knowledge of organic reactions and reaction mechanisms to carry out practical organic synthesis
• carry out synthesis corresponding to the level in "Organic Synthesis"
• carry out limited multi-step syntheses
• carry out synthesis under inert atmosphere
• describe and use different purification techniques
• determine the purity of the compounds synthesized using analytical and spectroscopic methods
• conduct literature searches in SciFinder
• explain and apply safe behavior in a synthetic laboratory

Subject overview
The following topics will be treated and discussed:

1. Precautions against accidents in the laboratory
2. Secure behavior in a synthetic laboratory
3. Use of SciFinder
4. Planning synthetic work
5. Different unit operations used in a synthetic laboratory
6. Preparation of selected organic and inorganic compounds

Literature

• Mikael Begtrup, Jan Becher og Mogens Brøndsted: Håndbog i organisk synteseteknik, Gyldendal, 2011.
• Jan O. Jeppesen, Stinne W. Hansen, Steffen Bähring, Niels Svenstrup & Jesper Lau: Institut for Fysik og Kemi, Syddansk Universitet, 2010.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
Attendance at laboratory exercises is a prerequisite for participating in the oral exam (exam b). Pass/fail, internal evaluation by teacher.

Assessment and marking:

1. Approval of compulsory reports with theoretical questions. Joint assessment. Passed/not passed, internal evaluation by a teacher (0 ECTS). Deadline for handing in reports and report forms will be posted on Blackboard
2. Oral exam with internal evaluation and marks according to the Danish 7-point marking scale (5 ECTS). Will be held immediately after the course. Date will be posted on Blackboard.

Re-examination right after the end of the course.

Date of exam
The ordinary exam takes place on January 18, 2016
The re-examination takes place on February 26, 2016

Expected working hours
The teaching method is based on three phase model.

Laboratory exercises (6 × 8 timer) and tutorials (2 hours).
Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Remarks
This course is taught in Danish and/or English.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.