KE510: Organic chemical analysis and separation (5 ECTS)

STADS: 10004101

Level
Bachelor course

Teaching period
The course is offered in the autumn semester.
The course takes place in the second half of the autumn semester.

Teacher responsible
Email: erik@sdu.dk

Timetable
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Show personal time table for this course.

Comment:
Samlæses med kandidatkurset KE822. Labhold for kandidater laves senere.

Prerequisites:
None

Academic preconditions:
Fundamental chemistry (KE501), Analytical spectroscopy (KE504) and Organic Chemistry (KE505) is assumed known.

Course introduction
The students should obtain practical skills in separating substance mixtures by using modern separation and purification techniques and obtain practical skills in identifying and determining the functional groups of organic substances. Through identification of IR, MS and 1H and 13C NMR spectra the students should be trained in practical analytical molecular spectroscopy including the interpretation problems implied in the fact that substances could be impure or poorly separated.

Expected learning outcome
By the end of the course the student should be able to:

• Use chemical methods for identification of organic compounds.
• Use spectroscopic methods for identification of organic compounds. 
• Use chemical and column chromatographic separation techniques. 
• Carry out small scale chemical reactions. 
• Find reference data on-line. 
• Knowledge of gaschromatography and HPLC.
• Estimate purity of a chemical sample.

Subject overview
Separation of substance mixtures by extraction and preparative column chromatography. Preparation of derivatives. Determination of functional groups and equivalent weight. HPLC and GLC analysis. Identification by MS, 1H and 13C NMR and IR spectra.

Literature

• Øvelsesvejledning, der placeres på Blackboard.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
Active participation in laboratory exercises and handing in two reports is a prerequisite for participating in the exam. Pass/fail, internal evaluation by teacher.

Assessment and marking:

1. Approval of report. Pass/fail, internal evaluation by teacher (5 ECTS).

Reexam in January.

The mode of the reeaxamination may differ from the mode of the ordinary examination.

Expected working hours
The teaching method is based on three phase model.
Intro phase: 1 hours
Skills training phase: 49 hours, hereof:
 - Laboratory exercises: 49 hours

Educational activities

Language
This course is taught in Danish.

Remarks
It is recommended that you do not attend this course after having completed your bachelor project in organic chemistry.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.