KE526: Applied heterocyclic chemistry (5 ECTS)

STADS: 10006301

Level
Bachelor course

Teaching period
The course is offered in the spring semester.
The course is primarily offered in the first half of the spring semester

Teacher responsible
Email: joj@sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 14-16 U166 7-12
Common I Tuesday 12-14 U151 6-7,10
Common I Thursday 12-14 U151 5
Common I Friday 08-10 U156 5-6,8-9,11
H1 TE Monday 16-18 U23A 7-12
H2 TE Tuesday 14-16 U90 7-12
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Comment:
Samlæses med KE823

Prerequisites:
None

Academic preconditions:
Students who attend the course are expected to:
  • be familiar with physical and organic chemistry including the structure and reactions of organic molecules as well as the concept of pH and thermodynamics.
  • have experience with the use of reaction mechanisms
KE505 Organic chemistry, KE521 or KE528 Basic inorganic chemistry as well as KE523 Physical Chemistry A are expected

Course introduction
The aim of the course is to make the students familiar with heterocyclic compounds and their importance in modern organic chemistry - including the synthesis of the most common heterocycles and their chemical properties.

The course is based primarily on the skills acquired in the second year course KE505 or equivalent with a systematic examination of the organic chemistry. The course is based on the fact that the students are in the third or fourth year of studies for a degree in chemistry, pharmacy, or chemical engineering, so that they can relate the course to other disciplines in chemistry, for example spectroscopy, chemical engineering, physical chemistry, or inorganic chemistry.

In relation to the education competence profiles, the course has a particular focus on expanding and improving the students’ basis for planning organic sytheses and to apply reaction mechanisms within modern organic chemistry.

Expected learning outcome
The learning objectives of the course is that the student demonstrates the ability to:
  • provide names for simple aliphatic and aromatic heterocycles
  • use reaction mechanisms to predict the formation of selected heterocyclic compounds
  • explain and account for the reactivity of selected heterocyclic compounds
  • explain examples of applications of selected heterocyclic compounds in for example medicinal chemistry and supramolecular chemistry
Subject overview
The following main topics are contained in the course:
  • General nomenclature of heterocyclic compounds.
  • Synthesis and chemical properties of heterocyclic compounds including pyrroles, furans, thiophenes, various five-membered heterocycles with several heteroatoms, pyridines, diazines and annullated heterocycles.
  • Use of reactions mechanisms to account for the formation of heterocyclic compounds
  • Examples of applications of heterocycles in for example medicinal chemistry and supramolecular chemistry.
 


Literature
  • John A. Joule and Keith Mills: Heterocyclic Chemistry, 5th Edition.


Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
  1. Oral exam, grades according to the Danish 7-point grading scale, external examiner. (5 ECTS). (10006302).


Expected working hours
The teaching method is based on three phase model.
Intro phase: 30 hours
Skills training phase: 12 hours, hereof:
 - Tutorials: 12 hours

Educational activities
  • Self-study of the textbook
  • Written hand-in exercises
  • Repetition for the exam
Educational form
In the study phase, students are expected to work on their own with the textbook and examples herein. It also includes preparation of hand-in exercises as a key element in the study phase, and students can expect feedback from a teacher. The students are also expected to use part of the study phase to pick up on the content of training phase and to reserve a small amount of time for repetition for the oral exam.

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Remarks
  • The course is co-read with: the corresponding master course KE823. 
  • If you plan to attend both Applied heterocyclic chemistry (KE526/KE823) and Advanced organic synthesis (KE518/KE814) in your complete study program, we recommend that you first attend KE526/KE823 or that you attend the two courses simultaneously.


Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.