KE806: Advanced Synthetic Chemistry (5 ECTS)

STADS: 10003101

Level
Master's level course

Teaching period
The course is offered in the spring semester.

Teacher responsible
Email: snv@sdu.dk

Timetable
Show entire timetable
Show personal time table for this course.

Prerequisites:
None

Academic preconditions:
Bachelor’s degree in chemistry, pharmaceutical chemistry, pharmaceutical sciences, nanobioscience or chemical engineering. KE506 Synthesis must be passed.

Course introduction
To obtain knowledge of advanced synthetic techniques and methods.

Expected learning outcome
After having completed the course the student is expected to be able to:

• relate theoretical knowledge on synthetic reactions to practical execution of multistep synthesis as well handling of typical equipment
• application of classical and modern reactions for the synthesis of complex target molecules
• application of template controlled reactions for the synthesis of macrocyclic molecules
• handling of advanced laboratory equipment (e.g. microwave reactor)
• efficient characterization of target molecules and intermediates using modern analytical techniques (e.g. NMR, MS and ESR)
• conduct literature search using Beilstein and Scifinder databases as chemical search tools actively relate chemical knowledge to safety (e.g. highly flammable solvents or explosive gases like hydrogen)

Subject overview
A number of multistep syntheses are performed. Syntheses in inert atmosphere, syntheses with small amounts of substances, highly reactive compounds, organometallic compounds and the application of advanced equipment (e.g. microwave reactor) will be performed.

Literature

• Litteratur følger med den specifikke syntese (omfatter øvelsesvejledning på blackboard og originalartikler).: .

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Lab. work, pass/fail, internal examiner.

Reexamination in the same exam period or immediately thereafter.

Expected working hours
The teaching method is based on three phase model.
Intro phase: 2 hours
Skills training phase: 48 hours, hereof:
 - Laboratory exercises: 48 hours

Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Remarks
50 hours should be planned to fit in the 60 hours of laboratory open time. An organizational meeting will be held before the course start. Time and place for meeting will be advertised on elearn 3 weeks before course start.
This course is taught in both English and Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.