KO68: Medicinal Chemistry (6 ECTS)

STADS: 1003741

Level


Teaching period

Autumn semester.

Teacher responsible
Email: ulven@ifk.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Tuesday 10-12 U37 45-46
Common I Tuesday 10-12 U17 47-48
Common I Tuesday 10-12 U55 49-51
Common I Wednesday 14-16 U103 46
Common I Thursday 10-12 U9 45, 47-51
S1 TE Wednesday 08-10 U9 45-51
S1 TE Thursday 14-16 U10 36-41
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Prerequisites:
None

Academic preconditions:
Organic Chemistry A (KO 02 / iot: K-OKE1) is presupposed known. Knowledge of cell biology is presupposed.

Course introduction
To make the participants familiar with important aspects of medicinal chemistry.

Expected learning outcome


Subject overview
Introduction of important aspects of development and design of drugs, including leads and pharmacophors, structural activity relations (SAR and QSAR), pharmaco-kinetics, drug metabolism and prodrugs. Furthermore, drugs designed for various targets will be treated: receptors, ion channels, enzymes or nucleic acids as well as classes of drugs including antibacterial and antiviral drugs, anticancer drugs, cholinergie and adrenergic agonists and antagonists, beta-blockers, ACE inhibitors, opioates, antihistamines and anaestetics etc.

Literature
  • Graham L. Patrick: An Introduction to Medicinal Chemistry, 3rd Ed, Oxford, 2005 .


Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
Oral examination. Marks according to the Danish 7-point marking scale. External examiner. Examination in oppositional terms only after acceptance from the Study Board.

Date of exam
The ordinary exam takes place on January 14, 2008 and January 15, 2008 and January 16, 2008

Expected working hours
The teaching method is based on three phase model.

1-2 weekly double lessons per semester (54 lessons in total) consisting of lectures including plenary discussions and group work. Part of the group work will be based on recent publications and will be followed by student presentations.
Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.