SU517: Physiology and pharmacology for pharmacists – Module 2: Heart, vessels and kidneys (5 ECTS)

Group	Type	Day	Time	Classroom	Weeks	Comment
Common	I	Monday	10-12	U48A	12
Common	I	Monday	09-14	*Odense Lokalitet aftales 1	14	Eksamen
Common	I	Tuesday	14-16	U140	17
Common	I	Wednesday	12-14	U20	6
Common	I	Wednesday	08-10	U20	7,9
Common	I	Thursday	16-18	U20	6
Common	I	Friday	12-14	U20	5,8-10,17
Common	I	Friday	14-17	U150	11
H1	TE	Monday	10-12	U142	8,13
H1	TE	Monday	12-14	U130	18	Farm 2 su517
H1	TE	Monday	10-12	U153	19
H1	TE	Monday	09-10	U142	20	Evaluering
H1	TE	Monday	10-13	U142	20
H1	TE	Wednesday	12-14	U44	11
H1	TE	Wednesday	15-18	U27A	18
H1	TE	Friday	10-12	SUN UIT	11
H1	TE	Friday	10-12	*Odense Lokalitet aftales 10	11	UIT?
H2	TE	Monday	12-14	U153	19
H2	TE	Tuesday	08-10	U142	8
H2	TE	Tuesday	12-14	U142	11
H2	TE	Wednesday	15-18	U28A	18
H2	TE	Thursday	16-18	U142	18
H2	TE	Friday	12-14	*Odense Lokalitet aftales 10	11	UIT?
H2	TE	Friday	12-14	SUN UIT	11
H2	TE	Friday	10-12	U142	13
H2	TE	Friday	10-13	U142	20
H2	TE	Friday	15-16	U146	20	Evaluering

Students taking the course are expected to:

• Have knowledge of the basics of physics, chemistry and biochemistry

 

The aim of the course is to give students insight into the function of specialized cells of the human body under normal physiological conditions and in disease. This is important for being able to explain the effect of a pharmacological treatment on specialized cell types under normal physiological conditions and in disease. 

The course is based on the knowledge acquired in module 1, i.e. SU516, and provides a scientific basis for studying the modules 3 and 4 within the ‘Physiology and Pharmacology for Pharmacists’ course. It is also the basis for the course on Clinical pharmacology and therapeutics, which will be taught in the master's program.

With regard to the competence profile of the curriculum, it is the explicit focus of the course to:

Provide the competence to:

• combine the various disciplines in the natural sciences with the more application-oriented medical disciplines, in particular for resolving pharmacological problems and for the development of new drugs 

Provide skills to:

• acquire new knowledge effectively and independently and apply this knowledge in a critical way.
• perform analyzes using scientific methodology
• identify own deficits in knowledge and to structure own learning

Provide knowledge about:

• the theories and methods within the discipline
• knowledge acquisition and experimental methods in the pharmaceutical sciences and related fields.

 

The learning objectives of the course are that the student demonstrates:

• sufficient knowledge of the main molecular and cellular mechanisms for understanding structure and function of the organs (heart, vessels and kidneys).
• ability to distinguish between the main molecular mechanisms of drugs acting on diseases affecting the heart, vessels, and kidneys.

 

The following main topics are taught in the course:

Hemodynamics

Cardiac cycle

Cardiac output

ECG (electrocardiogram) 

Control of blood flow and pressure

Cardiac inotropic agents

Antiarrhythmic drugs

Vasodilators

Antithrombotic agents

Cardiac flow and related drugs

Clearance 

GFR (glomerular filtration rate) 

Fluid and electrolyte balance

Urine concentration

Kidney pharmacokinetics

Drug administration

Pharmacogenetics

Drug interactions

Individualized therapy

Diuretics

Antihypertensive drugs

 

• Self-study of the textbook
• Self-study after the introduction and training phase
• Repetition in preparation of the exam

 

The introduction phase consists of lectures, in which the students will get a brief introduction to the course topics and the way to achieve competences. This will be complemented by the study guide and the textbooks, which the students are expected to study independently.

 

During the training phase, the students will achieve competences in cardiovascular and renal anatomy, physiology and pharmacology. In the small classroom teaching, the students will work with assignments, which they will have to prepare at home. In cardio-lab, the students work independently with practical aspects of pharmacology. In the study phase, students are expected to work independently with textbooks and examples and exercises herein. They are expected to work in small groups as regards elaboration and presentation of “case” work. Finally, students are expected to use part of the study phase to work on assignments of the training phase and do some repetition for the written exam.