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SU517: Physiology and pharmacology for pharmacists – Module 2: Heart, vessels and kidneys (5 ECTS)

STADS: 29004801

Level
Bachelor course

Teaching period
The course is offered in the spring semester.

Teacher responsible
Email: jdemey@health.sdu.dk

Timetable
Group Type Day Time Classroom Weeks Comment
Common I Monday 15-17 U20 7
Common I Monday 10-12 U20 8,10,19-20
Common I Monday 16-18 U20 11
Common I Monday 09-12 U20 16
Common I Tuesday 08-10 U20 6
Common I Tuesday 10-12 U140 16
Common I Tuesday 08-10 U150 19
Common I Tuesday 10-12 U20 20
Common I Wednesday 16-18 U20 12
Common I Friday 08-10 U20 5
Common I Friday 12-17 U154 18 MCQ test
Common I Friday 12-17 U24 18 MCQ test
Common I Friday 12-17 U155 18 MCQ test
Common I Friday 12-17 U156 18 MCQ test
H1 TL Tuesday 14-16 SUN UIT 17
H2 TL Tuesday 12-14 SUN UIT 17
H2 TE Tuesday 08-10 U152 17
H2 TE Thursday 12-14 U14 9
H2 TE Thursday 12-14 U20 15
H2 TE Thursday 12-14 U154 20-21
H2 TE Thursday 12-15 U64 22
H2 TE Friday 14-16 U131 12
H3 TE Monday 16-18 U152 17
H3 TE Tuesday 16-18 U31 9
H3 TE Tuesday 12-14 U9 15
H3 TL Tuesday 10-12 SUN UIT 17
H3 TE Tuesday 14-16 U31 20-21
H3 TE Tuesday 15-18 U64 22
H3 TE Thursday 12-14 U20 15
H3 TE Friday 16-18 U131 12
H3 TE Friday 08-10 U14 21
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Prerequisites:
None

Academic preconditions:
Students taking the course are expected to:
  • Have knowledge of the basics of physics, chemistry and biochemistry
 


Course introduction
The aim of the course is to give students insight into the function of specialized cells of the human body under normal physiological conditions and in disease. This is important for being able to explain the effect of a pharmacological treatment on specialized cell types under normal physiological conditions and in disease. 

The course is based on the knowledge acquired in module 1, i.e. SU516, and provides a scientific basis for studying the modules 3 and 4 within the ‘Physiology and Pharmacology for Pharmacists’ course. It is also the basis for the course on Clinical pharmacology and therapeutics, which will be taught in the master's program.

With regard to the competence profile of the curriculum, it is the explicit focus of the course to:

Provide the competence to:
  • combine the various disciplines in the natural sciences with the more application-oriented medical disciplines, in particular for resolving pharmacological problems and for the development of new drugs 
Provide skills to:
  • acquire new knowledge effectively and independently and apply this knowledge in a critical way.
  • perform analyzes using scientific methodology
  • identify own deficits in knowledge and to structure own learning
Provide knowledge about:
  • the theories and methods within the discipline
  • knowledge acquisition and experimental methods in the pharmaceutical sciences and related fields.
 


Expected learning outcome
The learning objectives of the course are that the student demonstrates:
  • sufficient knowledge of the main molecular and cellular mechanisms for understanding structure and function of the organs (heart, vessels and kidneys).
  • ability to distinguish between the main molecular mechanisms of drugs acting on diseases affecting the heart, vessels, and kidneys.
 


Subject overview
The following main topics are taught in the course:
  • Cardiovascular system: anatomy 
  • Cardiovascular system: physiology
    • Hemodynamics
    • Cardiac cycle
    • Cardiac output
    • ECG (electrocardiogram)
    • Control of blood flow and pressure
  • Cardiovascular system: pharmacology
    • Cardiac inotropic agents
    • Antiarrhythmic drugs
    • Vasodilators
    • Antithrombotic agents
    • Cardiac flow and related drugs
  • Renal system: anatomy
  • Renal system: physiology
    • Clearance
    • GFR (glomerular filtration rate) 
    • Fluid and electrolyte balance
    • Urine concentration
  • Renal system: pharmacology
    • Kidney pharmacokinetics
    • Drug administration
    • Pharmacogenetics
    • Drug interactions
    • Individualized therapy
    • Diuretics
    • Antihypertensive drugs
 


Literature
  • Linda Constanzo: Physiology, 5th edition, Elsevier.


Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
  1. Introduction and presentation of case. The prerequisite examination is a prerequisite for participation in exam element a). Pass/fail, internal examination by teacher. (29004812).
Assessment and marking:
  1. Løbende evaluering: 2 skriftlige delprøver (2 timers varighed hver) uden hjælpemidler. Samlet vurdering, der bedømmes med karakter (7-trin skala) og intern censur. Hjælpemidler ikke tilladt. Nærmere beskrivelse af eksamensreglerne vil blive offentliggjort under 'Course Information' på kursets side i BlackBoard. (5 ECTS). (29004802).
Reeksamen afholdes som en samlet eksamen.

Expected working hours
The teaching method is based on three phase model.
Intro phase: 21 hours
Skills training phase: 15 hours, hereof:
 - Tutorials: 11 hours
 - Laboratory exercises: 4 hours

Educational activities
  • Self-study of the textbook
  • Self-study after the introduction and training phase
  • Repetition in preparation of the exam
 
Educational form
The introduction phase consists of lectures, in which the students will get a brief introduction to the course topics and the way to achieve competences. This will be complemented by the study guide and the textbooks, which the students are expected to study independently.
 
During the training phase, the students will achieve competences in cardiovascular and renal anatomy, physiology and pharmacology. In the small classroom teaching, the students will work with assignments, which they will have to prepare at home. In cardio-lab, the students work independently with practical aspects of pharmacology.

In the study phase, students are expected to work independently with textbooks and examples and exercises herein. They are expected to work in small groups as regards elaboration and presentation of “case” work. Finally, students are expected to use part of the study phase to work on assignments of the training phase and do some repetition for the written exam.
 


Language
This course is taught in Danish or English, depending on the lecturer.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.