SU802: Medical neurobiology (5 ECTS)

STADS: 29000801

Level
Master's level course

Teaching period
The course is offered in the autumn semester.
1st quarter.

Teacher responsible
Email: jzimmer@health.sdu.dk

Timetable
Show entire timetable
Show personal time table for this course.

Prerequisites:
None

Academic preconditions:
Bachelor degree in biomedicine, pharmaceutical chemistry or medicamental science

Course introduction
To provide the students with the necessary knowledge about the normal structural and functional organization of the central nervous system (CNS) in order for the students to understand common diagnostic and therapeutic principles for important central nervous diseases.
To present topics of neuroscience research and methods to the students to provide a basis for critical evaluation of present knowledge and to stimulate continued education and research interest.

Expected learning outcome
At the end of course the student is expected to be able to account for:

• the gross anatomy of the central nervous system (CNS)
• the cellular components of CNS and the general functions of neurons and glial cells
• the meninges and CNS blood supply
• the cerebrospinal fluid production and circulation
• the electrochemical properties of neurons, incl. initiation and propagation of action potentials (nerve impulses)
• signal transduction in the synapse, incl. neurotransmitter and –transmitter functions and possibilities for modulation of these
• spinal cord and brain stem afferent and efferent connections and the neuronal basis for most important reflexes
• the peripheral somatosensory and visceral sensory receptors and propagation of somatosensory information from the periphery to the cerebral cortex
• the special senses (vision, hearing, balance, taste, smell) and the propagation of the sensory information from the peripheral receptors to the cerebral cortex, and the most important special sense reflexes
• examples of sensory malfunctions of clinical importance
• the structural and functional organization of the motor pathways from cerebral cortex to muscle
• the functioanl interaction between primary cortical motor areas and other cortical areas
• the structural and functional organization of the basal ganglia and connected brain areas
• the structural and functional organization of the cerebellum
• examples of motor malfunctions of clinical importance
• the structural and functional organization of the thalamus and the cerebral cortex
• modulation of cerebral cortical activity and the neural background for consciousness and sleep, incl. the arousal system of the brain stem
• mapping of brain activity by electrophysiological means and regional cerebral blod flow imaging
• cognitive functions, incl. language, perception of space and self and personality
• the structural and functional organization of the hypothalamus, incl.functional relations to endocrine system, the autonomous nervous system and somatic cortical functions
• the structural and functional organization of the limbic system and the neural basis for emotions, motivation and learning and memory
• examples of neocortical and limbic malfunctions of clinical importance

Subject overview
Cellular neurobiology, incl. basal neurophysiology og neurotransmission CNS gross anatomy and blod supply Spinal cord structural and functional organization with emphasis on spinal reflexes and sensory and motor pathways Structural and functional organization of the brain stem, thalamus and cerebral cortex Sensory systems, incl. special senses (vision, hearing, balance, taste, smell) Motor systems, incl. basal ganglia and cerebellum Hypothalamus, neuroendocrine control and autonomic functions The limbic system, emotions, learning and memory Cerebral cortex, cortical functions, consciousness/arousal and sleep

Literature

• Per Brodal: Sentralnervesystemet, 4 udgave, 2007 Universistetsforlaget AS; Oslo. .

Syllabus
See syllabus.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
None

Assessment and marking:
(a) Written exam. Danish 7 mark scale, external examiner.

Reexam after 2nd quarter.

Expected working hours
The teaching method is based on three phase model.

Forelæsninger, antal timer 32.
Eksaminatorietimer og gruppearbejde, antal timer 16.
Laboratorieøvelser, antal timer 4.

Laboratorieøvelserne består af praktiske studier af CNS præparater og eksempler på strukturel og funktionel billeddannelse af hjernen. Adgang til præparater og digitalt billed materiale i studiesal og via internet.
Educational activities

Language
This course is taught in English, if international students participate. Otherwise the course is taught in Danish.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.