English

BB523: Pharmaceutical Toxicology A (5 ECTS)

STADS: 04014001

Level
Bachelor course

Teaching period
The course is offered in the spring semester.

Teacher responsible

Email: Følger.

Timetable

Group	Type	Day	Time	Classroom	Weeks
Common	I	Monday	10-12	U48A	10
Common	I	Monday	08-10	U50A	15
Common	I	Tuesday	10-12	U48A	10
Common	I	Tuesday	12-14	U24	13
Common	I	Tuesday	08-10	U48A	14
Common	I	Thursday	12-14	U55	16
Common	I	Friday	10-12	U110	10
Common	I	Friday	12-14	U51	11
Common	I	Friday	12-14	U24	13
Common	I	Friday	08-10	U48A	15
H1	TE	Monday	10-12	U17	16
H1	TE	Tuesday	12-14	U23A	11
H1	TL	Tuesday	10-14	Yellow Lab	18-19
H1	TE	Wednesday	14-16	U51	13
H1	TL	Wednesday	10-14	Yellow Lab	20
H1	TE	Thursday	11-13	U51	14
H1	TE	Thursday	10-12	U17	15
H1	TL	Thursday	08-12	Yellow Lab	17
H2	TE	Monday	14-16	U10	16
H2	TE	Tuesday	12-14	U10	15
H2	TE	Wednesday	10-12	U23A	11
H2	TE	Wednesday	12-14	U51	13
H2	TL	Wednesday	10-14	Yellow Lab	18
H2	TL	Wednesday	14-18	Yellow Lab	19-20
H2	TE	Friday	14-16	U51	14
H2	TL	Friday	08-12	Yellow Lab	17
H3	TE	Tuesday	14-16	U157	13
H3	TE	Tuesday	14-16	U23A	16
H3	TL	Tuesday	14-18	Yellow Lab	20
H3	TE	Thursday	12-14	U14	11,15
H3	TE	Thursday	14-16	U51	14
H3	TL	Thursday	14-18	Yellow Lab	17
H3	TL	Thursday	10-14	Yellow Lab	19
H3	TL	Friday	10-14	Yellow Lab	18

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Prerequisites:
None

Academic preconditions:
Students enroled 2012 or later:
FF500, FF503, BMB504, BMB530, SU514 and KE527 assumed to be known.

Students enroled before 2012:
BB508, BMB501, BMB530, SU514, BMB504 and KE501 assumed to be known.

Course introduction
To introduce basic toxicological terms and analytical tevhniques

Expected learning outcome
After participation in the course the student is expected to be able to:

Describe the toxic mechanisms of model compounds on the physioloical and molecular level
Evaluate chromatographic data from the litterature, conduct chromatographic analysis

Subject overview

Dose-response relationships
Uptake, distribution, metabolism and excretion of xenobiotica
the P450 system – Phase 2 detoxification 
Toxic mechanisms (biochemical/molecular level)
cytotoxicity, genotoxicity, cancerogenity, teratogenity, liver toxicity and kidney toxicity
lung toxicity

   In the laboratory analytical techniques relevant for toxicology is introducedc: Chromatographic techniques as HPLC and gel eletrophoresis.

Literature

Oplyses senere.

Website
This course uses e-learn (blackboard).

Prerequisites for participating in the exam
Active participation in laboratorials are mandatory, presence at min. 80% of the meetings. (04014012)

Assessment and marking:
4 hours written, digital exam; External censorship; grades according to the Danish 7-mark scale. (04014002)

Reexamination in the same exam period or immediately thereafter.

Expected working hours
The teaching method is based on three phase model.
Intro phase: 20 hours
Skills training phase: 26 hours, hereof:
- Tutorials: 10 hours
- Laboratory exercises: 16 hours

Educational activities Study phase: 50 hours

Language
This course is taught in Danish or English, depending on the lecturer.

Course enrollment
See deadline of enrolment.

Tuition fees for single courses
See fees for single courses.